T-joints of TC4 and TA15 titanium alloys have been welded by continuous wave laser beam.The effect of weld parameters on weld appearance and shearing resistance of the joints have been analyzed using metalloscope and tensile testing machine. The experimental results showed that when other parameters were fixed, the weld width and depth of skeleton was improved with the increase of laser beam power and decrease of weld speed. The weld width of skeleton was the determining parameter of shearing resistance of laser welding T-joints. With the laser beam power over 4.1 kW, weld speed less than 80 mm/s and defocusing amount between -5 and +10 mm, the weld depth of skeleton reached 0.51 mm, the shearing resistance of the joints reached 14 kN.