Continuous carbon fiber reinforced polymer composites is a key structural material in the area of aerospace and aviation. To add nano materials with excellent properties into composites could upgrade the mechanical performance of the materials. This report introduces the recent development of fabrication method of carbon nanotube-carbon fiber multiscale reinforcement, such as chemical vapor deposition, chemical grafting and electrophoretic deposition. The effect of carbon nanotube on the interface of the composites is also presented. In conclusion, electrophoretic deposition would be a cost-effective, efficient and mass productive method in the preparation of carbon nanotube-carbon fiber multiscale reinforcement.