Based on the SPH method simulated process that the corrugation obliquity of stuffed corrugation-cored sandwiches is 30°,45°,56° and 60° impacted by space debris,and hypervelocity impact protection characteristics was compared,so,the corrugation obliquity of stuffed corrugation-cored sandwiches effect on hypervelocity impact protection characteristics was studied. The results show that expansion degree of debris cloud by impact is increscent by corrugation obliquity,and when the corrugation obliquity is 56°that the damage stuffed corrugation-cored sandwiches to space debris is the most bad; the difference of no-reversible work that four kinds structure translated is little,that show,corrugation obliquity effect on the no-reversible work transform is lesser；the damage in the spacecraft wall that be protect by different corrugation obliquity stuffed corrugation-cored sandwiches is different,when the corrugation obliquity is 56°that damage in the spacecraft wall is least,so,the protection characteristics is best in the four kinds corrugation obliquity structure.