Aiming at the problems of high cutting force,high cutting temperature and low surface quality when carbide tool was used to milling AISI304 stainless steel with high speed internal cooling.Based on the response surface center composite test design method,the high-speed internal cooling milling test was carried out, and the second-order regression forecast model of each milling force component was established and verified by experiments. The surface quality after dry milling and internal cooling milling was compared.The influence of milling parameters on the milling force components was analyzed,and the milling parameters were optimized with minimum milling force components as the goal.The results indicate that the error between the predicted value and the experimental value of the feed force and the radial force are 4.77% and 6.16%,respectively.The Ra value of internal cooling milling is 0.193 to 0.327 µm.The influence on milling components is milling depth>rotation speed>feed rate, the feed force first increases and then decreases with increasing milling depth and speed,the radial force increases gradually, the interaction between milling depth and speed have a significant influence on feed force and radial force.The optimal milling parameter combination are that speed is 11 643.63 r/min,milling depth is 1 mm,and feed rate is 0.08 mm/r.