In the process of disc milling grooving in blisk,the milling force is large and the milling temperature is high,these factors will form a deep residual stress layer on the machined surface,which will seriously affect the fatigue life of the parts.In order to improve the fatigue life of parts,based on the titanium alloy block as the research object,the surface residual stress is measured by the residual stress test analysis system,and the subsurface residual stress is studied using the dial layer method.The linear regression technique is adopted to establish the prediction model of residual stress,and the range analysis method is used to analyze the influence law of process parameters on the residual stress.The test results show that the residual compressive stress are generated on the machined surface caused by extrusion effect,and the residual stress on hub surface is greater than that on the convex/concave surface. The significance level of the regression prediction model is 0.01,and the regression effect is good.The influence degree of each factor on σ_Ax 、σ_Ay （σ_Ax 、σ_Ay represent residual stress in x and y directions of hub surface respectively) is spindle speed＞feed speed＞depth of cut (DOC) respectively.The influence degree of each factor on σBx (σBx refers to residual stress in the x direction on the convex/concave surface) is in turn spindle speed＞DOC＞feed speed respectively.The longitudinal residual stress is compressive stress,the distribution depth on the hub surface is 230 to 270 μm,and the distribution depth on the convex/concave surface is 170 to 175 μm.