Through tensile shear test of the aerospace adhesive J-47, the effects of factors such as base adhesive air-drying time, curing pressure, adhesive film moisture absorption, heating rate, and bagging method on bond strength were systematically studied. Results indicate that the air-drying time of primer with 35%~45% solids content has negligible impact on the tensile shear strength of medium-temperature cured adhesive film specimens, rendering it unsuitable for characterizing the bonding performance of large-area honeycomb sandwich structural components. With the increase of curing pressure, the tensile shear strength of specimens first rises, then stabilizes, and finally decreases. The maximum tensile shear strength is achieved at curing pressures between 0.15 and 0.3 MPa. The tensile shear strength of the specimens decreases with increasing moisture ingress time into the adhesive layer before stabilizing. At a moisture content of 1.47%, the tensile shear strength reaches its lowest value, decreasing by 20.78% compared to the initial state. Selecting appropriate additives and controlling the heating rate within the range of 0.5~3 °C/min can yield high tensile shear strength.