W-Ti[w(Ti)=10%] alloy was prepared, and the influence of powder purity and W powder size on the density and microstructure of W-Ti[w(Ti)=10%] alloy was studied. It is found that the higher the purity of powder, the higher the density of W-Ti[w(Ti)=10%] alloy, and the lower the Ti rich phase proportion. The W-Ti[w(Ti)=10%] alloy with 3N purity will retain pure Ti, and the proportion of Ti-rich phase is 31.28%. The W-Ti[w(Ti)=10%] alloy with 4N and 4N5 purity does not have pure Ti, and the proportion of Ti-rich phase is 28.41% and 21.67%, respectively. The influence of W powder particle size is reflected in two aspects: the larger the W powder particle size, the better the mixing effect with Ti powder, the more conducive to diffusion; but the smaller the specific surface area, the less conducive to diffusion. With the increase of W particle size, the Ti-rich phase content of W-Ti[w(Ti)=10%] alloy decreases first and then increases. In this experiment, when the particle size of W powder is 4~5 μm and the particle size of Ti powder is 44 μm, the microstructure properties of W-Ti[w(Ti)=10%] alloy are the best, and the proportion of Ti-rich phase is 28.79%.