In order to solve the problem of selecting spacecraft materials， according to the working environment characteristics and properties of spacecraft materials， an index system for the applicability evaluation of spacecraft materials is established from the four aspects：functional stability， process applicability， environmental adaptability and service safety. The comprehensive evaluation model of spacecraft materials application validation is established through analytic hierarchy process （AHP） and entropy weight method. Two batches of coating materials for spacecraft are taken as examples， the comprehensive weight is determined by combining the subjective and objective methods through AHP-entropy weight combined method. Finally， the properties of two batches of spacecraft coating materials is scored and compared by using the fuzzy comprehensive evaluation method.