This paper prepared and evaluated an epoxy resin system (V601) and its composite materials for a low-cost vacuum assisted resin infusion (VARI) molding process. This paper evaluated the resin matrix and its composite materials through DSC curves, rheological curves, and mechanical tests. The results show that the V601 epoxy resin system can be completely cured under a curing system of 120 ℃/2h; the process applicability period of resin is long (viscosity ≤ 500 mPa·s, 225 min); the tensile strength of the resin cured material is 77.7 MPa, the tensile modulus is 3.25 GPa, the bending strength is 137.7 MPa, and the bending modulus is 3.37 GPa. The fiber volume content of SW280F/V601 composite material prepared by VARI method is 67.7%, the longitudinal tensile strength is 626 MPa, the longitudinal tensile modulus is 25.8 GPa, the longitudinal bending strength is 727.4 MPa, and the longitudinal bending modulus is 11.7 GPa. The results indicate that the V601 resin system has good applicability to VARI molding process, and the prepared composite materials also have high mechanical properties.