Lightweight multifunctional structure is an important technical route towards lightweight spacecraft equipment. This paper reviews the design and manufacture techniques for lightweight multifunctional spacecraft structures, focusing on the status and development trends in the following aspects: three-dimensional lattice structures with high load-bearing capacity, stable structures under thermal deformation, smart deployable structures, separation and unlocking structures, electromagnetic stealth structure, and novel connection techniques for composites. Critical technical issues faced by the development of novel spacecraft structures are briefly analyzed at the same time.