In order to explore the formation mechanism of surface defects such as delamination and chipping in milling of CFRP,the milling experiment of CFRP was carried out. Based on the single factor method,the influence of the fiber angle on the milling forces of CFRP was obtained. Using the central composite response surface method,the influence of milling speed,feed per tooth and milling width on the milling forces was analyzed,and the prediction models of the milling forces during the milling of CFRP were established. The experimental results show that the milling forces decrease with the increase of the fiber angle from 0° to 90°,while the milling force increase with the increase of the fiber angle from 90° to 180°. f_z and a_e have a significant influence on the three-direction milling forces. v_c has a significant influence on the y-direction and z-direction milling forces,while the influence on the x-direction milling force is not significant;the milling forces increase with the three milling parameters,and the feed per tooth has the greatest influence on the milling forces.