The physical simulation of 2219 Al-alloy was carried out by the Gleeble-3500 thermal simulation tester.Through stress-strain curves and microstructure observement,the heat plastic rheological behavior of 2219 Alalloy and its effect on spinning forming was studied. The results show that the rheological stress of 2219 Al-alloy during heat plastic deforming is mainly influenced by deforming temperature and strain rate,the effect of deformation rate is not obvious.The peak stress and steady state flow stress both reduces with improving temperature and dropping strain rate. It helps to achieve controlling shape during large scale 2219 Al-alloy component spinning forming by combining Gleeble physical simulation and process test. According to thermal simulation test result,spinning deformation is carried on 2219 Al alloy shell with spinning temperature from 300 to 350℃,feed rate from 0.6 to 1.5 mm/r and 30% deformation rate. Al alloy shell with good surface quality can be obtained with wall thickness under 0.2 mm and the unlaterial gap between inner profile and theoretical model under 0.1 mm.