The effects of selection of mold materials, processing of assembly and machining on the manufacturing of high precision CFC-made secondary reflector antenna were analyzed through researching the key assembly techniques, compared mold material, optimized assembly process and machining verification experiment.The results show that invar is an ideal mold material for the manufacturing of high precision CFC-made secondary reflector antenna. When the sandwich structure is assembled, adopting the in situ assembly technique for the external covering and individual adoption of the cellular around transitional region of the antenna covering can effectively avoid the poor surface accuracy of the antenna. A comprehensive application of an auxiliary mould for the machining and the 3D image measurement system can effectively ensure the high positional accuracy of the assembly reference point and significantly shorten the manufacturing period of the antenna.